Faqs 

Allergy drops, also known as sublingual immunotherapy (SLIT), are a form of treatment designed to reduce or eliminate allergic reactions over time. Instead of getting allergy shots (injections), patients place small doses of allergens under the tongue in drop form.

Allergy drops have been safely used worldwide for more than 60 years to treat allergy symptoms. They are gentle enough for infants, children, and individuals with chronic health conditions who cannot receive allergy shots.

Like allergy shots, allergy drops contain the same FDA‑approved antigens—the only difference is that the treatment is taken orally rather than by injection.

Allergy drops train the immune system to become less sensitive to allergens by introducing small amounts over time. Taken daily under the tongue, the drops contain gradually increasing doses of allergen extract. As tolerance builds, symptoms like sneezing, itching, and swelling often lessen—and may even disappear. For many patients, allergy drops provide long‑lasting relief and have been shown to be as effective as allergy shots.

Most patients are on allergy drops for 3-5 years.

Refine Allergy currently treats patients 18 years and older in the state of Oklahoma. If the patient resides outside the state of Oklahoma, they must be older than 

Contraindications include patients that are taking Beta Blockers or ACE Inhibitors. 

Other contraindications include patients with preexisting cardiac conditions, uncontrolled asthma, COPD, a history of anaphylaxis, HIV/AIDS, immunocompromised/chemotherapy patients, autoimmune diseases or utilizing immunosuppressants, Eosinophilic Esophagitis (EoE), Gastroenteritis, that are unable to communicate, or are pregnant. 

At Refine Allergy, we keep our pricing simple and upfront. A 3-month supply costs $255, making the average monthly cost $85.

*Allergy drops are cash pay only. We do not bill or accept insurance for this treatment.*

• Personalized formulation based on your allergy test results
• Compounding and preparation of your drops by a licensed pharmacy
• Allergy immunotherapy drop supply for approximately 12 weeks (3 months)
• Direct access to our allergy nurse for questions, concerns, or treatment guidance throughout your therapy
• Direct shipping to your home for convenience

While insurance may cover the cost of your testing through your primary care provider, there are currently no insurances that cover sublingual allergy immunotherapy drops.

Consistency is key when it comes to allergy drops. If you miss a day or more, do not try to “catch up” by taking more than the prescribe two drops in a single day.

• If you miss 2–14 days, simply resume your drops as directed.

• If you miss more than 14 days, contact us before starting again.

Please contact us immediately. You will need to reorder your allergy drops to avoid a delay in treatment.

Once on maintenance dose (this starts when you receive your second order), you will take 2 drops under the tongue daily. Hold the drops under your tongue for approximately 30 seconds before swallowing.

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